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The second is an anti-androgen, to neutralize the testosterone she is producing.”“Doesn’t that mean continuing with the histrelin?” Sierra asked.“It’s a different mechanism. Ideally we’d like to use an androgen synthesis inhibitor. These stop the production of testosterone, but those drugs are either breathtakingly expensive or still in development. The one that’s approved is fifty thousand a year.”“That’s worse than the histrelin,” Glenn replied.“Exactly. Instead we start with an androgen antagonist. These block the action of the testosterone she produces, and are quite reasonably priced. Our first line is spironolactone. It’s a daily pill, available as a generic and costs only about twenty dollars a month.”“That’s quite a bit more reasonable,” Glenn remarked. “If it’s generic, there’s no co-pay. The insurance will cover it all.”“It’s well tolerated, however the drug’s primary use is to treat congestive heart failure or fluid buildup. Its anti-androgen properties are actually. " I'll be with you, Jim."I looked at the seriousness in Kristen's eyes. "I know you will. Would you really like to live a musician's life?"Kristen shrugged. "I'd be a musician's wife. It's not the same." No," I said, shaking my head. "You misunderstood me. Would you like to live a musician's life?" Me? A musician?" Kristen laughed.She saw the serious look in my eyes. "Yes, you." Why?" I've seen you play. I've seen you help Amy. You get almost as much joy out of music as I do, and you put less than a tenth of the effort that I do." Me?" Kristen was completely taken by surprise."You become a musician--a millionaire musician," I said, smiling. "I'll become one as well. Together, we can redefine music together." The two of us?" Kristen said.From the look that Kristen gave me, it occurred to me that she never even considered this option.I found one of my best male friends in the hallway the next day. "Roy? I need help with a female singer."Roy looked at me strangely. "The musical is over,.
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